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The retina is the most vascular region in the body as it needs high oxygen to convert light into electrical energy in the rods and cones Chronic hyperglycemia may cause microvascular damage to the retinal vessels resulting in edema and/or hemorrhage into the retina or the vitreous humor because of vascular permeability In fact dysglycemia often occurs earlier than the.

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McMartin KE Ambre JJ Tephly TR Methanol poisoning in human subjects Role for formic acid accumulation in the metabolic acidosis Am J Med 1980 68 (3)414–8 101016/00029343(80)901138 [Google Scholar].