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Phosphorylation fluctuates during the cell cycle with a moderate peak during G1 phase and weakens the binding of DEK to DNA1 Publication Manual assertion based on experiment in i Ref9 “Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEK” Position (s)Description ActionsNacetylserine Combined sources Manual Phosphothreonine Combined sources Manual Phosphothreonine By similarity Phosphoserine Combined sources Manual.
DEK Protein DEK Homo sapiens (Human) DEK gene & protein
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7913 Gene ResultDEK DEK protooncogene [ (human)]
DEK can contribute directly to joint inflammation in juvenile idiopathic arthritis by generating ICs through highaffinity interaction between DEK and DEK autoantibodies DEK overexpression partly through an increase in its gene dose mediates the activity of global transcriptional regulators and is associated with tumor initiation activity and poor prognosis in high grade neuroendocrine.
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